Herein, we present a 24-year-old patient who presented 40 h after the consumption of 50 grams of paracetamol.
Early use of activated charcoal, an increased dose of NAC, and early hemodialysis are suggested for a massive overdose of paracetamol. 2 N-acetylcysteine (NAC) is the antidote of choice in paracetamol poisoning. 7 Acute ingestion is defined as any intentional or deliberate paracetamol overdose, including staggered or multiple paracetamol ingestions over more than 2 h. 6A paracetamol overdose is considered massive when the intake of paracetamol is ≥30 grams. 4, 5Īcute ingestion of at least 7.5–10 gms in adults or 150–200 mg/kg in children above 6 years is considered a toxic dose of paracetamol, which is likely to produce hepatotoxicity. 3 Paracetamol poisoning can be fatal owing to its hepatotoxic and nephrotoxic nature.
1, 2Paracetamol was also the single most used drug for acute poisoning in India.
Paracetamol poisoning accounts for the majority of overdoses in Europe, North America, and Australia. Paracetamol or acetaminophen is an over-the-counter antipyretic and analgesic drug notorious for intentional and accidental self-poisoning.
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